泰国 NIC IVF 生殖中心

NIC IVF 生殖中心是由Matchuporn玛祖教授（博士生导师）和Warawun瓦拉婉博士（研究生导师）带领一群在辅助生殖和遗传基因学领域有着丰富经验的医生和科研人员共同成立。前期医生会充分了解每一位患者不同的诉求和身体状况，然后针对每个患者制定不同因人而异的诊疗方案，在相互配合、信任、愉快的气氛中，实现每个家庭生儿育女的心愿。为了每个患者的成功，除了常规的基因和辅助生殖技术外，NIC还提供了多种的的医疗技术，具体如下。

NIC IVF clinic is established by Assistant Professor Dr. Matchuporn Sukprasert, Dr. Warawun Lupthalug and experienced medical technicians whose specialties revolve around genetic and reproductive medicine. In order to accomplish our patient goal, we firstly emphasize our understanding in each patient. This enab us not only to treat each patient difficulty properly but also to fulfill each family requirements pleasurably (PATIENT). In addition to general clinical practices found in common IVF facilities, we convey our passion through special medical techniques. This is to provide the best suitable remedy specifically for each case. These techniques are as of followings.

医院环境：

Macs 辅助生殖优选精子分离技术

Macs 是一种辅助生殖优选精子分离技术。这项技术能够在受精前，通过激活的凋亡信号(死亡细胞)分离出优质活力的精子。这项技术与传统的精子分离技术比，极大的提高了试管的成功率。

This is a technology that optimizes sperm separation in assisted reproduction. It helps separating sperm with activated apoptosis signaling (dead cell) before entering fertilization process. This results in enhanced clinical pregnancy rate comparing to an old technique which cannot distinguish the sperm.

Halosperm技术

Halosperm技术可以使DNA降解的精子变得可视化，这项技术可以高效、快捷地为胚胎医师提子DNA碎片的诊断，挑选出优质的精子。经过挑选的优质精子不但极大提高卵子的受精率，同时也提高了胚胎的着床率。

This technique allows the visualization of sperm that contains highly degraded DNA compared to other sperm. It is a fast, simple and cost-effective method that provides an IVF doctor to exae sperm DNA fragmentation easily. Therefore.

the good quality sperm selection could be obtained for a fertilization process. This could increase a fertilization rate and embryo implantation rate accordingly.

ERA 基因检测技术

ERA 是一项独特的针对子宫内膜容受性状态的基因检测技术，这项技术针对每个移植患者不同状况并结合女性不同的生理周期，检测评估出患者移植前期子宫内膜接受胚胎植入的较佳状态，从而推断出一个准确的合适的移植时间。ERA检测可以精确的安排每对夫妻的移植时间，并极大程度的提高胚胎移植成功率和妊娠率。

ERA is a genetic test that evaluates the state of endometrial receptivity, which is the optimal time for embryo transfer. It diagnoses the time that a uterus is ready to receive the embryo. Since implantation period for each woman is different. The ERA test enab us to personalize embryo transferring time for each couple accurately. This greatly increases a chance of successful embryo transfer rate and pregnancy rate.

Spindle view技术

Spindle view技术是通过高倍的智能电子显微镜，胚胎师在进行单精子注射受精(ICSI)时，能够清晰的看到卵子纺锤体，从而避免伤害并保护了卵子纺锤体。这项技术让胚胎师从传统的通过个人经验上的判断纺锤体位置，提升到可以直观的看到纺锤体位置，避免伤及卵子纺锤体，从而极大提高了卵子受精率和优质胚胎率。

This computerized high power microscope technology enab a doctor or an embryologist to see spind of retrieved eggs when perforg Intracytoplasmic sperm injection (ICSI). This is to avoid corrupting the egg spind when injecting sperm cell into the egg. Therefore, a successful chance of fertiliza- tion becomes higher comparing to one without Oosight technique which the doctor or embryologist can perform the ICSI procedure merely from educated guess.

PGT-M(单基因病检测）

PGT-M(单基因病检测），PGT-M是为每一对有遗传基因疾病风险的夫妇提供独有的检测方案，避免了下一代的相关遗传疾病。遗传疾病例如：地中海贫血、亨廷顿病、杜氏肌营养不良病、血友病等等。

PGT-M这种特殊的技术必须由拥有雄厚的生殖遗传学背景，专业性极强的医生全程独立实施完成。在NIC的临床医疗团队里，Matchuporn教授是泰国第一位在这一特定领域的医生，她同时也是美国威尔康奈尔医学院的一名科研人员。Matchuporn教授和NIC的实验室科研人员，随时准备为任何可能与单基因遗传疾病有关的夫妇提供相关咨询，并尽心尽力为每一位遗传病辅助生殖患者提供专业的诊疗。

Preimplantation Genetic Testing for monogenic disease (PGT-M): The PGT-M are created uniquely for each family or each fertile couple who has a risk of transmitting a genetic

disorder to their offspring. The genetic disorder includes, for example, Thalassemia, Huntington disease, Duchenne Muscular Dystrophy, Hemophilia and etc. This exceptional technique must be solely performed by a doctor who is a specialist and graduated from Reproductive Genetic. One of our clinic team, Assistant Professor Dr. Matchuporn Sukprasert is the first doctor in Thailand who graduated in this particular field. She was a fellow from Weill Cornell Medical College, Cornell University, New York, United states. She and our scientists are ready to consult willingly with any couple who is possibly related to monogenetic diseases.

NGS技术

NGS技术的运用可以在较短的时间内筛查24条染色体或人类全基因组测序。通过这项技术，在植入前进行胚胎基因诊断，挑选优质的胚胎进行移植。相较于FISH技术（仅可以用于筛查5对染色体），NGS可以显著地提高怀孕的成功率。

This is a testing technique that screens all 24 chromosomes or whole-genome human sequencing in the least amount of time. This particular method, when applied to pre-implantation process, allows a doctor or scientist to select only embryos with a normal chromosome profile to transfer. This could yield to a higher chance of effective pregnancy rate comparing to Fluorescence in situ hybridization (FISH) technique which is able to screen only 5 pairs of chromosomes.

NIC的实验室和手术室

除此之外，NIC的实验室和手术室都是通过了1000级洁净实验室标准的审核。1000级实验室标准是目前试管婴儿医院实验室中较高级别。NIC结合以上数项的技术和先进的设备，确保整个诊疗过程都是在较先进的实验室和手术室中进行，同时NIC的医生也将竭尽所能，来完成患者的心愿和保持NIC的高成功率。因为我们始终相信，健康聪明的孩子不但是家庭完整的基础，同时也可能是社会富强的基础。

Furthermore, our operating room and laboratory are certified as CLASS 1000 cleanroom. This is the cleanest level for an IVF process and highly preferable compared to regular IVF clinics. Together with all advanced techniques prescribed previously, this ensures that we always practice our treatment in an exceptional modern laboratory and utmost environment. Since our goal is to obtain an effective curing process and optimize a pregnancy rate (PASSION). Because we all strongly believe that healthy children will complete your family which is an important foundation to achieve strong and quality society (POSSIBILITY).